Phenylmercury Transport Mediated by merT-merP Genes of Pseudomonas K-62 Plasmid pMR26.
نویسندگان
چکیده
منابع مشابه
Evaluation of ppk-specified polyphosphate as a mercury remedial tool.
To evaluate the utility of polyphosphate kinase gene (ppk)-specified polyphosphate in mercury remediation, a fusion plasmid, pMK27, with ppk from Klebsiella aerogenes and mercury transport genes, merT and merP, from Pseudomonas K-62, was constructed. The transcription and translation of ppk, merT and merP were found to be mercury-inducible. The ppk-specified polyphosphate was identified in cell...
متن کاملRole of MerC, MerE, MerF, MerT, and/or MerP in resistance to mercurials and the transport of mercurials in Escherichia coli.
The characteristics of bacteria take up mercury into cells via membrane potential-dependent sequence-divergent members of the mercuric ion (Mer) superfamily, i.e., a periplasmic mercuric ion scavenging protein (MerP) and one or more inner membrane-spanning proteins (MerC, MerE, MerF, and MerT), which transport mercuric ions into the cytoplasm, have been applied in engineering of bioreactor used...
متن کاملMercury operon regulation by the merR gene of the organomercurial resistance system of plasmid pDU1358.
The structural basis for induction of the mercury resistance operon with inorganic mercury and with the organomercurial compound phenylmercuric acetate was addressed by DNA sequencing analysis and by lac fusion transcription experiments regulated by merR in trans from broad-spectrum-resistance plasmid pDU1358 (Hg2+ and phenylmercury responding). The lac fusion results were compared with those f...
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Pseudomonas aeruginosa is a leading cause of bum infections, and antibiotic- resistant strains of this bacterium are emerging due to extensive application of antibiotics in the bum unit of hospitals. In this study 50 strains of P. aeruginosa were isolated from bum patients infected with this micro-organism in the bum unit of a general hospital in Kerman, Iran over one year [May 1999-ApriI20...
متن کاملThe metabolism of phenylmercury by the rat.
The metabolism of [U-(14)C]phenylmercury acetate was studied in the rat. After a single subcutaneous dose a small proportion is excreted unchanged in urine, and a larger amount in bile with some resorption from the gut. The greater part of the dose is broken down in the tissues to yield inorganic mercury which is excreted mainly in faeces, and conjugates of phenol and quinol are excreted in uri...
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ژورنال
عنوان ژورنال: Biological and Pharmaceutical Bulletin
سال: 1997
ISSN: 0918-6158,1347-5215
DOI: 10.1248/bpb.20.107